Cancer-associated adipocytes and fibronectin matrix

Mammary acini

Engineered microvessel

α-SMA staining of mouse prostate and peri-prostatic fat

Recent News

Peter DelNero received a Cornell Engaged Graduate Student Grant and a Buttrick-Crippen fellowship to enhance public awareness and communication related to cancer. Congratulations!

Research Areas

Microenvironmental conditions (e.g., 3-D cell-cell and cell-extracellular matrix interactions) are critically important in tumor induction and progression, and mediate the establishment of metastases at preferential target sites. By exploring diversified tissue-engineered model systems and polymeric growth factor delivery strategies, our research aims at elucidating microenvironmental events that currently impair the prognosis of cancer patients and to develop new drug delivery systems for more effective treatment of cancer.

Recent Publications

Springer N. L., Fischbach C., Biomaterials Approaches to Modeling Macrophage-Extracellular Matrix Interactions in the Tumor Microenvironment, Current Opinion in Biotechnology, 2016 (40):16-23.